Description
Product Characteristics:
Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).[supplied by OMIM, Mar 2008].
Synonyms: Adenylyl-sulfate kinase, Adenylylsulfate 3''-phosphotransferase, APS kinase, ATP-sulfurylase, ATPSK 1, ATPSK1, Bunctional 3' phosphoadenosine 5' phosphosulfate synthetase 1, PAPS synthase 1, PAPS synthetase 1, PAPS1_HUMAN, PAPSS 1, PAPSS, PAPSS1, SAT, SK 1, SK1, Sulfate adenylate transferase, Sulfurylase kinase 1, 3 prime phosphoadenosine 5 prime phosphosulfate synthase 1, 3' phosphoadenosine 5' phosphosulfate synthase 1, 3''-phosphoadenosine-5''-phosphosulfate synthase, Adenosine-5''-phosphosulfate 3''-phosphotransferase.
Target Information: Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).[supplied by OMIM, Mar 2008]